Stay informed

Here you'll find regular updates on what's new at Kleijnen Systematic Reviews Ltd.

KSR staff are heading to the Global Evidence Summit 2017

A number of KSR staff have been successful in their applications for sessions at the Global Evidence Summit to be held in Cape Town in September 2017.

 

Ching-Yun Wei, Regina Leadley, Sohan Deshpande, Ciara Keenan and Lisa Stirk will all have posters; Robert Wolff will have a short oral presentaion; Shelley de Kock and Robert Wolff will have long oral presentations and Robert Wolff will also have a workshop.

 

KSR will also have a stand at the conference, so hope to see you there!

KSR training course

KSR staff delivered a very successful four-day course on "Systematic reviews of economic evaluations and cost data; health technology assessments and the use of the ROBIS checklist" for a team of researchers from Jimma University, Ethiopia.  The course was hosted at our offices in York on 8-11May 2017.

Report recommending NIHR funding for UK Cochrane entities published

The report “Evaluation of NIHR investment in Cochrane infrastructure and systematic reviews” by a Committee chaired by Professor Jos Kleijnen was published in March 2017.

 

The report can be found here.

KSR appoints a Deputy Director

Robert Wolff MD, has been appointed Deputy Director at Kleijnen Systematic Reviews Ltd.  Robert has worked at KSR for nine years, having joined as a systematic reviewer in 2008 and promoted to reviews manager in 2013.   Robert will assist Jos Kleijnen to further promote and expand KSR’s interests and work in the field of evidence based medicine and systematic reviews.

 

For more information about Robert, please see Robert Wolff.

Systematic Reviewing Retreat

Professor Jos Kleijnen and Professor Maurice Zeegers will teach a three day systematic reviews course from 14-16 June 2017 at Monastery Rolduc, the Netherlands.

 

For more information on the course and how to book, please click here.

 

KSR awarded 'Best poster presentation EAHIL first-time attendee' at EAHIL, Seville 2016

At this year's EAHIL (European Association for Health Information and Libraries) Conference in Seville Shelley de Kock won the best poster first-time attendee for:

 

de Kock S, Misso K, Stirk L, Westwood M, Deshpande S, Kleijnen J, McLellan A, Kleijnen J. Developing a database of critically appraised systematic reviews in the field of pain management. Paper presented at 15th EAHIL Conference; 6-11 Jun 2016; Seville, Spain.

KSR Evidence poster EAHIL 2016
KSR Evidence Poster EAHIL 2016.pdf
Adobe Acrobat document [369.6 KB]

For details of the proceedings, click here.

 

At the same conference Steven Duffy gave two presentations:

 

Duffy S, Misso K, de Kock S, Noake C, Ross J, Stirk L. Supplementary searches of PubMed to improve currency of MEDLINE (Ovid) searches for systematic reviews: time taken for record to move to MEDLINE. Paper presented at 15th EAHIL Conference; 6-11 Jun 2016; Seville, Spain. 2016: Oral E7.

Presentation

Proceedings

 

Duffy S, Ross J, Misso K, de Kock S, Noake C, Stirk L. Is it possible to focus EMTREE without loss of sensitivity when searching Embase for systematic reviews? Analysis of Cochrane Reviews and HTA reports. Paper presented at 15th EAHIL Conference; 6-11 Jun 2016; Seville, Spain. 2016: Oral G1

Presentation

Proceedings

KSR staff present at GIN Conference, Amsterdam 2015

Jos Kleijnen was Chair of the Scientific Committee for this year's GIN Conference, held in Amsterdam 8-10 October 2015.

 

Robert Wolff gave a presentation at the same conference: PROBAST: Prediction model risk of bias assessment tool

R Wolff GIN 2015
GIN 2015 - PROBAST.pdf
Adobe Acrobat document [1.5 MB]

KSR has a large presence at the Cochrane Colloquium, Vienna 2015

KSR sent a large team to this year's Cochrane Colloquium in Vienna.  They ran one workshop, presented four papers and had two posters.  Robert Wolff was also co-chair of the abstract committee.

 

Workshop:

Wolff R, Whiting P, Moons K. Systematic reviews of prognostic studies 1: assessing risk of bias in studies of prediction models using the PROBAST tool. Workshop at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Workshop W57.

R Wolff workshop W57
Cochrane workshop W57.pdf
Adobe Acrobat document [1.3 MB]

 

Oral presentations:

Deshpande S, Misso K, Stirk L, Westwood M, Kleijnen J, McLellan A, et al. Introducing KSR Evidence: developing a database of critically appraised systematic reviews in the field of pain relief. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Rapid Oral 5.4.

S Deshpande rapid oral 5.4
Cochrane rapid oral 5.4.pdf
Adobe Acrobat document [474.5 KB]

Duffy S, Ross J, Misso K, Noake C, Stirk L. Is it possible to focus EMTREE without loss of sensitivity when searching Embase for systematic reviews? Evidence from practice. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Rapid Oral 23.4.

S Duffy rapid oral 23.4
Cochrane rapid oral 23.4.pdf
Adobe Acrobat document [131.6 KB]
S Duffy rapid oral 23.4 references
Cochrane rapid oral 23.4 references.pdf
Adobe Acrobat document [56.0 KB]
S Duffy rapid oral 23.4 tables
Cochrane rapid oral 23.4 tables.pdf
Adobe Acrobat document [53.0 KB]

Stirk L, Duffy S, Misso K, Noake C, Ross J. Supplementary searches of PubMed to improve currency of MEDLINE and MEDLINE In-Process searches via Ovid: evidence from practice. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Rapid Oral 23.7.

L Stirk rapid oral 23.7
Cochrane rapid oral 23.7.pdf
Adobe Acrobat document [382.2 KB]

Wolff R, Whiting P, Mallett S, Riley R, Westwood M, Kleijnen J, et al. PROBAST: a risk of bias tool for prediction modelling studies. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Rapid Oral 1.7.

R Wolff rapid oral 1.7
Cochrane rapid oral 1.7.pdf
Adobe Acrobat document [947.8 KB]

 

Posters:

Misso K, Stirk L, Westwood M, Deshpande S, Kleijnen J, McLellan A, et al. Finding systematic reviews on pain: building the KSR Pain Evidence database. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Poster P2-118.

K Misso poster P2-118
Cochrane Poster P2 118.pdf
Adobe Acrobat document [381.1 KB]

Riemsma R, Birnie R, Armstrong N, Duffy S, Worthy G, Kleijnen J. Type-1-diabetes: the problems associated with comparing Integrated Sensor-Augmented Pump Therapy systems for managing blood glucose levels with multiple daily injections. Paper presented at 23rd Cochrane Colloquium; 3-7 Oct 2015; Vienna, Austria. 2015: Poster P2-092.

R Riemsma poster P2-092
Cochrane poster P2 092.pdf
Adobe Acrobat document [286.6 KB]

KSR Pain Evidence Database

KSR has launched the first in a series of databases which will critically appraise all systematic reviews in various topic areas.  The first database to be launched is KSR Pain Evidence.  For more information, click here.

Cannabinoids for medical use - a systematic review and meta-analysis

KSR staff have published a systematic review of cannabinoids for medical use.  The journal article about this report has been published in JAMA - see here for details of publication.  See the Q&A document below for more information about this work and publication.  For details of the full report, please click here.

Cannabis General QA.pdf
Adobe Acrobat document [313.0 KB]

Workshop on systematic reviews

Professor Jos Kleijnen led a workshop on systematic reviews at the European Congress of Epidemiology 2015: Healthy Living (Maastricht, The Netherlands, 25-27 June 2015). 

 

KSR team present at Cochrane Colloquium, Hyderabad, September 2014

The KSR team ran two workshops, presented three papers and had one poster:

 

[1] Wolff R, Whiting P, Mallett S, Riley R, Westwood M, Kleijnen J, et al. PROBAST: introduction to a new risk of bias tool for prediction modelling studies. Workshop at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Workshop 60.

 

[2] Whiting P, Savovic J, Shea B, Reeves B. An opportunity to learn more about and pilot ROBIS, a new tool to assess the risk of bias in a systematic review. Workshop at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Workshop 07.

 

[3] Wolff R, Whiting P, Mallett S, Riley R, Westwood M, Kleijnen J, et al. Prediction study risk of bias assessment tool (PROBAST). Paper presented at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Oral session 03.4.

 

[4] Whiting P, Wolff R, Savovic J, Mallett S. Introducing LATITUDES: a library of assessment tools and instruments used to assess data validity in evidence syntheses. Paper presented at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Oral session 05.1.

 

[5] Whiting P, Savovic J, Higgins J, Shea B, Reeves B, Caldwell D, et al. ROBIS: a new tool to assess the risk of bias in a systematic review. Paper presented at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Oral session 05.4.

 

[6] Armstrong N, Deshpande S, Riemsma R, Kleijnen J. Non-comparable patients in non-randomised comparative studies: misleading study design? Poster presented at 22nd Cochrane Colloquium; 21-26 Sep 2014; Hyderabad, India. 2014: Poster 72.

 

For details of the presentations, please visit the Colloquium website.

For details of the poster, please click below.

Poster 2014 Cochrane Colloquium
P72- Cochrane Colloquium 2014-Sohan Desh[...]
Adobe Acrobat document [522.2 KB]

KSR’s contract with NIHR to provide evidence reviews to NICE has been extended

KSR has been awarded a further five year contract with the National Institute for Health Research (NIHR) to provide Technology Assessment Reviews for the National Institute for Health and Care Excellence (NICE) from 2016 to 2021.

 

KSR’s founder and Director, Professor Jos Kleijnen states “This is excellent news for KSR and NIHR’s decision to renew and increase our contract until 2021 confirms KSR’s status as a Centre of Excellence”

 

For information on our work with NIHR, click here.

KSR staff attend inaugural ISSG workshop

 

Kate Misso and Lisa Stirk attended the inaugural UK InterTASC Information Specialists' Sub-Group Workshop, held on 9th July at the University of Exeter.  Click here for further information. 

 

The Workshop was convened to bring together information professionals, reviewers and economists working on the field of health technology assessment (HTA). Attendees came from academia, consultancies, research institutes, NICE and industry, to discuss and share their views and experiences working on technology appraisals.

 

The KSR Information Team presented two posters at the workshop, investigating two information retrieval topics:

 

[1] Supplementary searches of PubMed to improve currency of MEDLINE and MEDLINE In-Process searches via OvidSP.

Duffy S, Misso K, Noake C, Ross J, Stirk L. (2014) Kleijnen Systematic Reviews Ltd, York

Link

 

[2] Is it possible to focus EMTREE without loss of sensitivity when searching Embase for systematic reviews?

Duffy S, Ross J, Misso K, Noake C, Stirk L. (2014) Kleijnen Systematic Reviews Ltd, York

 

ISSG Exeter 2014 poster 1.pdf
Adobe Acrobat document [755.1 KB]
ISSG Exeter 2014 poster 2.pdf
Adobe Acrobat document [498.8 KB]

Targeting the cause of cystic fibrosis

 

KSR staff have recently completed a report on the use of Ivacaftor for the treatment of patients with cystic fibrosis and the G551D mutation. 

 

For the full report, click here.   For information on our work for NIHR, click here.

 

Authors: Whiting P, Al M, Burgers L, Westwood M, Ryder S, Hoogendoorn M, Armstrong N, Allen A, Severens H, Kleijnen J

Journal: Health Technology Assessment Volume: 18 Issue: 18

Jos Kleijnen awarded professorship at Maastricht University

Jos has become Professor of Systematic Reviews in Healthcare at CAPHRI: the School for Public Health and Primary Care at Maastricht University.  

 

Kleijnen Systematic Reviews Ltd has been declared a "Centre of excellence" for TARs by the National Institute for Health Research (NIHR)

Three new centres of expertise in Technology Assessment Reviews (TARs) join seven existing NIHR TAR centres. TARs provide a reliable and rigorous evidence assessment of the benefits, harms and costs of particular healthcare treatments for those who plan, provide or receive care in the NHS.

TARs are commissioned to meet the urgent needs of national NHS decision-making bodies and policy customers, such as the National Institute for Health and Clinical Excellence (NICE). TARs are most commonly produced to inform NICE Appraisal Committee guidance on the use of new and existing medicines, treatments and procedures within the NHS in England and Wales.